Abstract: When the sulfate reducing bacteria (SRB) is used to treat a groups of acid mine drainage (AMD),the low pH and high concentration of heavy metal ions inhibit the treatment. Using PVC and boric acid,adding 30% SRB sludge,5% corn cobs,5% iron and 15% of modified and unmodified Maifan stone,the No. 1 and No. 2 immobilized particles were made respectively to research the No. 1 and No. 2 particles regarding their dynamic and adsorption capaci- ty,and the treatment process of No. 1 particles on SO24- ,Mn2+ in different initial concentrations of SO24- ,Mn2+ ,and H+ . The results show that the SO24- reduction process by No. 1 and No. 2 particles is in line with the first order kinetics,the maximum reduction rate of No. 1 particles is 88. 2 mg / (L·h),which is greater than No. 2 particles with 82． 4 mg / (L· h). The level 2 dynamic model can describe No. 1 and No. 2 particles on the adsorption mechanism of Mn2+ well. The No. 1 and No. 2 particles on Mn2+ isothermal adsorption model is better in accord with the Freundlich equation. There- fore,the alienation reduction SO24 with modified Maifan stone immobilized particles- is better,and the competition ad- sorption effect between cation is less. The initial concentration of SO24- by changing system of COD / SO24- and particle concentration difference inside and outside influences the metabolic process of immobilized particles,the metabolic properties of the particles affected by the concentration of Mn2+ is less,and the resistance to pH impact is good.