Abstract: In order to study the evolution law of fault damage and slip under the mining effect, combined with microseismic monitoring, a fault damage variable was introduced to evaluate the risk of fault slip.Sensitivity analysis was conducted to evaluate the factors that affect the fault damage variable by orthogonal simulation test.The results show that the fault damage and slip is divided into three stages:fault damage initiation, fault damage propagation and fault slip.With the working face close to the fault, the fault damage variable gradually increases.Fault damage variables are affected by mining factors, fault factors and in-situ stress level.Among the mining factors, the distance from the fault and the inclined length of working face are highly significant influence factors, while mining thickness has no obvious effect.Among the fault factors, fault dip angle and fault friction angle are highly significant influence factors, fault cohesion is generally significant, and other fault factors have no obvious effect.The influence of lateral pressure coefficient on the fault damage variable is higher than that of buried depth.