Abstract: Indirect coal liquefaction technology ( ICLT) can realize the clean utilization of coal,which has become an effective way of oil replacement and the clean utilization of coal. The operation results of industrial demonstration and preliminary commercialization of ICTL indicate that the scale-development of ICTL is restricted by some bottlenecks, including unsatisfactory catalyst performance,low capacity per Fischer-Tropsch ( F-T) reactor,unqualified gasoline and diesel products,synthetic water transferred to salty wastewater. To solve the above problems,the National Energy Group undertook the national key research and development project-“ Advanced Indirect Coal Liquefaction and Prod- uct Processing Technology Development“ . This paper summarized the research progress of the project in detail,in- cluding: ① Through the in-situ crystal transfer technology mediated by Co2 C,carrier optimization,engineering scale- up research,and the pilot-scale catalyst preparation of 10 kg / batch was achieved. The targets of ≥0. 3 kg oil /( kg catalyst·h) C+ space-time yield,≥90% CO conversion rate,and ≥6 000 h single regeneration life of the cat- alyst were obtained on the pilot plant with upgraded catalyst capacity. The cobalt-based catalyst for slurry F-T syn- thesis was qualified for industrial application trial. ② The active phase formation mechanism of the iron F-T catalyst was systematically studied by in-situ / ex-situ technologies. 1 t / d catalyst production was achieved based on the labo- ratory recipe finalization and scale-up research. The catalyst showed ≥1. 0 kg-oil / ( kg-catalyst · h) space time yield and ≤1. 0 kg catalyst consumption per ton oil from the 100 t-oil / year pilot plant test. The iron-based catalysts for slurry F-T synthesis is applied into megaton industry units. ③ The gas-solid fluidized bed reactor applied for the activation of iron-based F-T catalyst. The basic design of 20 t / batch gas-solid fluidized technology was completed. ④ A two-phase interaction model based on the EMMS theory was established. A CFD-PBM model was developed based on the simulation of slurry FTS reaction and hydrodynamics studies. The technical reform plan for 650 000 tons / year capacity expansion was confirmed. ⑤ Research units and methods for the magnetic separation of F-T slag wax were established. A 20 L / h magnetic separation experiment was completed with 0. 02% Fe content after separation. ⑥ The hydrocracking catalyst research and process development for gasoline product from F-T synthetic wax have been fi- nalized in laboratory. ⑦ 5 L / batch diesel was reconciled using diesel components produced by million tons scale di- rect / indirect coal liquefaction industrial units. The diesel fuel blending component research achieved the desired target based on a 5 L / batch blending experiment with diesel fuel component from megaton units of direct / indirect coal lique- faction. ⑧ The de-acidification of F-T synthetic water by membrane separation was well studied in laboratory. The al- cohols extraction and separation technology for F-T synthetic water was exploited in pilot-scale test. The test of F-T synthetic water treated as boiler water after alcohol extraction to meet the resource utilization of F-T synthetic water was completed. The project has started from scientific issues diagnosis and executed to overcome the technology bottle- necks,the developed technologies being and to be commercialized have all been verified by pilot test. Next,it is to for the production of G6 gasoline / diesel.